topics in graph colouring and extremal graph theory
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New pH responsive polymersomes for active anticancer oligonucleotide delivery were prepared from triblock copolymers. The delivery systems were formed by two terminal hydrophilic blocks, PEG and polyglycerolmethacrylate (poly GMA), and a central weakly basic block, polyimidazole hexyl methacrylate (poly ImHeMA), which can complex with oligonucleotides and control vesicle formation/disassembly via pH variations. Targeted polymersomes were prepared by mixing folate derivatized and underivatized copolymers.
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